RNA localization is a powerful strategy used by cells to localize proteins to subcellular domains and to control protein synthesis regionally. In germ cells, RNA targeting has profound implications for development, setting up polarities in genetic information that drive cell fate during embryogenesis. The frog oocyte offers a useful system for studying the mechanism of RNA localization. Here, we discuss critically the process of RNA localization during frog oogenesis. Three major pathways have been identified that are temporally and spatially separated (...) in oogenesis. Each pathway uses a different mechanism to effect RNA localization. In some cases, localization elements within the 3' untranslated region have been identified and have provided unique insights into the localization process. This important field is still in its infancy, however, and much remains to be learned. BioEssays 21:546–557, 1999. © 1999 John Wiley & Sons, Inc. (shrink)

This paper focuses on the ethical and moral implications of findings from the authors? national survey of television news directors? policies, practices, and perceptions of good/bad news. In light of the potentially negative effects of excessive amounts of bad news on individuals and society, the authors ask whether television journalists have an ethical responsibility?beyond legal constraints and professional criteria?in the selection and presentation of bad news and good news. An earlier version of this paper, detailing the findings of the survey, (...) was presented to the Radio?TV Journalism Division of the Association for Education in Journalism and Mass Communication in August, 1986. (shrink)

Abstract‘Cruel optimism’ is a term coined by Lauren Berlant. In conceptualizing this term, Berlant draws on the resources of critical theory to interrogate people’s desires for things they think may improve their lot, but actually act as obstacles to flourishing. This notion may be useful for analysing the current state of education in Australia, and the desire to believe that My School, and the associated data it provides, will enable schools to address social inequalities. For Berlant, the promise of such (...) technologies is problematic because it diverts our attention from important ethical, social and political questions, some of which are highlighted in the contributions to this special issue. Using ‘cruel optimism’ as a point of departure, I interrogate how the notion of critical theory has been conceptualized in educational research by briefly looking at scholarship within and outside education relating to critical theory. Following on from this, I consider how what I am terming critical theory is put to work in each of the articles that make up this special issue on My School. (shrink)

This book engages contemporary debates about the notion of secularism outside of the field of education in order to consider how secularism shapes the formation of progressive sexuality education. Focusing on the US, Canada, Ireland, Aotearoa-New Zealand and Australia, this text considers the affinities, prejudices, and attachments of scholars who advocate secular worldviews in the context of sexuality education, and some of the consequences that ensue from these ways of seeing. This study identifies and interrogates how secularism infuses progressive sexuality (...) education. It asks readers to consider their own investments in particular ways of thinking and researching in the field of sexuality education, and to think about how these investments have developed and how they shape existing discourses within the field of sexuality education. It hones in on how progressive sexuality education has come to develop in the way that it has, and how this relates to conceits of secularism. This book prompts a consideration of how "progressive" scholarship and practice might get in the way of meaningful conversations with students, teachers, and peers who think differently about the field of sexuality education. (shrink)

If ‘a’ and‘b’are (proper) names and if the meaning of a name is exhausted by its referent, how can‘a = a’differ in cognitive value from‘a = b’if‘a = b’is true? This is Frege's famous puzzle and Bezuidenhout reconstructs it using demonstrative NPs in place of names, i.e.: This X is that X.’Her solution is to posit the‘truth-conditional relevance’of the de re modes of presentation of such expressions. My major objection is that Bezuidenhout's examples are such that the NP to the (...) right of the copula is anaphoric rather than demonstrative and cannot, therefore, support her argument. (shrink)

To find more information on Rowman & Littlefield titles, please visit us at www.rowmanlittlefield.com.

To find more information on Rowman & Littlefield titles, please visit us at www.rowmanlittlefield.com.

_The Cultural Politics of Queer Theory in Education Research_ represents the editors’ intention to disrupt cycles of thinking about the place of queer theory in educational research. The book aims to encourage dialogue about the objects and subjects of queer research, the forms of politics incited by the use of queer theory in education, and the methodological approaches used by scholars when queering. The contributions to this book come from those who find queer theory problematic, as well as from those (...) who continue to see a productive place for queer research in education, however that may be defined. The editors have collected contributions that attend to the boundaries that are placed around queer research in education by researchers themselves, and by peers, ethics committees, funding bodies and university and government bureaucracies. Considering how key researchers in gender and education identify with, or deliberately distance themselves from, queer theory, this collection grapples with the contemporary cultural politics of doing queer theoretical work in different education spaces and places. In short, it seeks to disrupt what people think they already know about the ‘place’ of queer theory in education. This book was originally published as a special issue of _Discourse: Studies in the Cultural Politics of Education. _. (shrink)

Teaching in university education programmes, can, at times, involve the uncomfortable situation of discriminatory speech.A situation that has often occurred in our own teaching, and in those of our colleagues, is the citation of homophobic and heterosexist comments.These are comments that are more likely to occur in foundation subjects such as philosophy and sociology of education.The occurrence of such situations has prompted debate regarding ‘silencing words that wound’. This has prompted the question, ‘should we keep students from stating such discriminatory (...) speech?’ Our article takes up this issue, and considers it from the perspective of the importance of critique.Working with Foucault’s What is Critique? together with his discussion of subjectivation in the 1981–82 lectures at the Collège de France, we set out to make the case for the significance of the relationship between truth and critique.This leads us to a position where we ask the question, if we silence, what do we risk doing to critique? (shrink)

In the next few years, biotechnology will continue to develop a wide variety of functional foods, foods whose benefits go well beyond basic nutrition. Minors are a major potential market for bioengineered foods that are promoted not as sustaining health but rather as supporting desired lifestyles through the enhancement of physical, athletic, intellectual, or social performance. The experience of other industries suggests that such biomarketing is likely to create a variety of highly public ethical controversies. After a discussion of some (...) of these potential issues, suggestions on how companies and industries can work with marketing ethicists and child advocates to limitnegative impacts on children and youth are presented. That discussion includes a preliminarily analysis of some of the considerations that should be involved in the initial development of a model of biomarketing ethics and in the use of that model to prevent ethical abuses. (shrink)

Ce texte s’inscrit dans le prolongement d’un effort endurci pour penser les modalités complexes du dialogue entre la psychanalyse lacanienne et la phénoménologie française dans la seconde moitié du xx e siècle. Plus exactement, il s’agit ici d’indiquer les raisons objectives, à la fois théoriques et pratiques, qui expliquent la violence de la réception française du De l’interprétation de Paul Ricœur, en mettant en perspective les positions respectives du philosophe et celles du psychanalyste Jacques Lacan lors du colloque de Bonneval (...) sur l’Inconscient d’octobre 1960. L’analyse détaillée du texte “Le conscient et l’inconscient” – élément du corpus ricœurien trop souvent négligé – au regard de l’enseignement lacanien du tournant des années 1960 doit en outre permettre de dégager deux théories de l’interprétation antagonistes, afin d’indiquer pour finir les points concrets de divergence entre les orientations “ricœurienne” et “lacanienne” de la clinique psychanalytique. (shrink)

Working memory deficits are pervasive co-morbidities of epilepsy. Although the pathophysiological mechanisms underpinning these impairments remain elusive, it is thought that WM depends on oscillatory interactions within and between nodes of large-scale functional networks. These include the hippocampus and default mode network as well as the prefrontal cortex and frontoparietal central executive network. Here, we review the functional roles of neural oscillations in subserving WM and the putative mechanisms by which epilepsy disrupts normative activity, leading to aberrant oscillatory signatures. We (...) highlight the particular role of interictal epileptic activity, including interictal epileptiform discharges and high frequency oscillations in WM deficits. We also discuss the translational opportunities presented by greater understanding of the oscillatory basis of WM function and dysfunction in epilepsy, including potential targets for neuromodulation. (shrink)

This paper explores violence in intimate relationships in one low-income community in the Western Cape, South Africa. In this community most intimate relationships (including parentchild, intimate partner relationships and friendships) seem to be characterized by anger, rage and also violence. In our analysis we discuss how the concepts of shame, guilt and the compulsion to repeat can serve to illuminate the seemingly inevitable link between violence and care in this specific community. It also seems that contextual factors such as class, (...) gender and race shape not only the form violence assumes, but also to whom it is directed. While we pay attention to the material and ideological conditions that shape the lives of individual storytellers, we also focus on the ways in which violence is represented in the individual stories. (shrink)

The primary subject of this study is the assessment ofJohann B. Metz’s judgment that Karl Rahner’s transcendental anthropology abstracts from concrete experience and succumbs to a kind of Idealist tautology. Secondarily consideration is given to the broader range of similar criticisms of Rahner’s construal of the God-human relation.

This study aims to characterise Human Research Ethics Committee (HREC) members’ perceptions on five main themes associated with ethics reviews, namely, the nature of research, ethical/moral issues, assent, participants’ risk and HREC prerogatives issues. Three hundred and sixteen HREC members from over 200 HRECs throughout Australia responded to an online questionnaire survey. The results show that in general, HREC members’ beliefs are reasoned and align with sound principles of ethical reviews. There seems to be a disposition for living up to (...) ethical/moral values, avoiding the issue of consent waivers and respecting participants’ welfare, as well as a sense of ambiguity about HREC prerogatives. Problematic areas were a tendency towards over-valuing quantitative research methods for their perceived validity and a neutral view on issuing consent waivers to participants with intellectual disability and, finally, the belief that research that limits disclosure, plans deception or actively conceals is morally unjustifiable. Implications for professional development and policy-making are discussed. (shrink)

The purpose of this article is to examine empirically the impact of environmental certification on firm financial performance (FP). The main question is whether there is a "green premium" for certified firms, and, if so, for what kind of certification. We analyze the short-run and the long-run stock price performance using an event-study methodology on a sample of Canadian and U.S. firms. The results of short-run event abnormal returns indicate that forest certification does not have any significant impact on firm (...) FP regardless of the certification system carried out by firms. Unlike the short-run results, the long-run post-event abnormal returns suggest that forest certification has, on average, a negative impact on firm FP. However, the impact of forest certification on firm FP depends on who grants the certification, since only industry-led certification (Sustainable Forestry Initiative, Canadian Standards Association and ISO14001) are penalized by financial markets, whereas non-governmental organizations—led Forest Stewardship Council certification is not. (shrink)

Cet article constitue la présentation des recherches effectuées par une équipe franco-grecque sur le tell de Kirrha en Phocide entre 2008 et 2015, et représente la publication préliminaire des structures archéologiques mises au jour. Deux secteurs distants l’un de l’autre ont été fouillés, révélant une dense occupation de l’Helladique Moyen, ainsi que des niveaux s’étageant jusqu’à l’Helladique Récent III. Notamment, une nécropole de la période transitionnelle (Helladique Moyen III – Helladique Récent I/II) a été fouillée dans la partie occidentale du (...) site, tandis que des niveaux mycéniens ont été reconnus à proximité du sommet. (shrink)

Joyce's review of _Humanism, Philosophical Essays: A Collection of Essays on Pragmatism_, by Ferdinand Canning Scott Schiller, was written at a critical moment in the development of Joyce's fiction (before "The Sisters", before the essay "A Portrait of the Artist," and during Joyce's writing of his aesthetic theory. The review was published in the _Dublin Express_ on November 12, 1903. The diary entries at the end of _A Portrait of the Artist as a Young Man_ hint at the fallibilism and (...) reality of experience at the bedrock of Peircean semiotics and the revolutionary style of Joyce. Unfortunately the mocking style of Joyce's review may be why it has not received attention and perhaps why the review has not been included in a recent collection of Joyce's non-fiction writings. Joyce mocks Schiller’s style and thought, which is "prone to stylistic violations such as: vulgarity ... excessively ornate language ... pomposity ... exaggeration ... and avoiding the issue" as Joseph Porrovecchio states in a dissertation on Schiller's rhetoric. Schiller not only provoked Joyce to mock him, he also provoked Charles Peirce, the founder of pragmatism, to rename his philosophy "pragmaticism" adding an "ic" to it to differentiate it from Schiller’s use of the word. This essay shows Joyce knew about Charles Peirce, whose influence was extensive, continuing through Finnegans Wake, as discussed in Roy Benjamin’s The Triptych Vision: Joyce and Peirce. (shrink)

& A college development officer is offered a generous gift by a donor whose identity would embarrass the institution. Should the development officer accept? & A volunteer lies about his level of giving, but classmates believe him and match his "gift." Should donors be told the truth? & A development officer must explain to a donor the difference between naming an endowed chair and selecting the person to fill the chair. Where is the line between reasonable donor expectations and intrusion? (...) "There was a time, barely a generation ago, when most college fund raising was a placid, back-porch operation... That pattern, like so much in higher education, began to change dramatically... On the heels of all this change comes this splendid volume by Deni Elliot. The new fund-raising environment raises a host of ethical questions that were largely unknown or unrecognized by earlier generations of fund raisers... The great value of this book is that it provides some clear-eyed guidance through the ethical thicket that is modern higher education fund raising. The great charm of the book is that it provides this important service with such eloquence and good taste... Anyone involved in modern fund raising will find something of value in this book." -- G. Calvin MacKenzie, Academe "This volume provides college and university development officers and administrators practical help with recognizing difficult ethical situations and discerning the correct ethical response. It can also serve as a guide for donors who wonder what's reasonable for them to expect from fund raisers." -- Resources in Education Contributors: Allen Buchanan, James A. Donahue, Marilyn Batt Dunn, Deni Elliott, Bernard Gert, Judith M. Gooch, Bruce R. Hopkins, Frank Logan, Mary Lou Siebert, Holly Smith, and Eric B. Wentworth. (shrink)

Resumen: El espacio dramático de Michel Tremblay, “tesoro nacional” de Quebec, está poblado por personajes que se enfrentan casi siempre a la alienación y al deseo de encontrar, o incluso de crear, su propia identidad. Los héroes tremblayanos, cualquiera que sea su orientación sexual y posición en la sociedad, realizan un paso desde la inactividad hasta la acción para desgajarse del orden preestablecido. A veces incapaces de cambiar su situación, a veces felices al poder, por fin, contestar a la pregunta (...) “¿quién soy yo?”, los personajes del teatro de Tremblay siguen siendo representativos de la sociedad quebequense que, durante el período de la llamada Revolución tranquila, se vio sometida a unos profundos cambios identitarios. A lo largo de la evolución social del Quebec de los años sesenta y setenta del pasado siglo, se fueron estableciendo paralelismos entre la toma de conciencia identitaria de la sociedad y la de los personajes dramáticos de Trembley. Así, estos últimos se convertirían en alegorías de la estructura social en por lo menos dos dimensiones, moral y cultural, en el caso de Belles-Sœurs y À toi, pour toujours, ta Marie-Lou, donde se incuban las frustraciones propias de unas heroínas abrumadas por la cultura patriarcal (impotente en todos los ámbitos y ante todo el sexual), representada a su vez por la pieza Hosanna, a la que se la puede considerar como el símbolo de la expresión social de la homosexualidad y de la identidad sexual en general. En consecuencia, la finalidad de este artículo sería la reflexión misma acerca de unas (r)evoluciones teatrales que reflejarían las llevadas a cabo por la Revolución tranquila dentro de toda la sociedad. Abstract: Michel Tremblay's dramatic space, Quebec’s “national treasure”, is populated by characters who are almost always confronted with alienation and the desire to rediscover, and even to create, their own identity. The heroes of Tremblay, whatever their sexual orientation and social positions are, have the story of a passage from inaction till the act of tearing themselves away from the pre-established order. Sometimes incapable of changing their situation, sometimes happy to finally be able to answer the question “Who am I?”, the characters in the Tremblayan theatre are at all times representatives of the Quebec society, which, during the Quiet Revolution, suffered profound changes in identity. Throughout the social evolution in Quebec in the 1960s and 1970s, the awareness of the identity of the society and that of the dramatic characters are two matters that coexist in parallel manner. Thus, the latter become allegories of the social structure on at least two levels: moral and cultural, in the case of the Belles-Sœurs and À toi, pour toujours, ta Marie-Lou representing several frustrations: of the heroines, overwhelmed by the powerless patriarchal culture; sexual, represented for example by Hosanna being the symbol of the social expression of homosexuality and sexual identity in general; and finally, actional, as in the case of Sainte Carmen de la Main, which constitutes a message to Québécois to take their destiny in their hands. The main objective of the article is to bring some reflections on theatrical (r)evolutions which reflected the changes of the Quiet Revolution within the entire society. (shrink)

Today, many visual artists are giving the cold shoulder to the static, isolated concept of visual art and searching instead for novel, dynamic connections to different image strategies. Because of that, visual art and aesthetics are both forced to reconsider their current positions and their traditional apparatus of concepts. In that process, many questions surface. To mention a few: Could the characteristics of an artistic image and its specific manner of signification be determined in a world which is entirely aesthetisized? (...) What would be the consequences of a variety of image strategies for aesthetic experience? Would it be possible to develop a form of cultural criticism by means of artistic activities in a culture awash in images? In order to answer such questions, aesthetics as a philosophy of art needs to transform its field into a critical philosophy of topical visual culture. As an impetus to such a reinterpretation of the visual working area, the L & B Series organized three symposia evenings under the title “Exploding Aesthetics”, in cooperation with De Appel Center for Contemporary Art, Amsterdam. Besides the presentations and discussions from these symposia, this volume includes various arguments, positions, and statements in both articles and interviews by a variety of visual artists, designers, advertising professionals, theorists and curators. The participants are: Mieke Bal, Annette W. Balkema, Peg Brand, Experimental Jetset, Liam Gillick, Jeanne van Heeswijk, Martin Jay, KesselsKramer, Friedrich Kittler, Maria Lind, Wim Michels, Nicholas Mirzoeff, Planet Art, Joke Robaard, Annemieke Roobeek, Remko Scha, Rob Schröder, Henk Slager, Richard Shusterman, Pauline Terreehorst, Wolfgang Welsch and Marie-Lou Witmer. (shrink)

The #metoo movement has forced many fans to consider what they should do when they learn that a beloved artist has acted immorally. One natural thought is that fans ought to give up the artworks of immoral artists. In Why It's OK to Enjoy the Work of Immoral Artists, Mary Beth Willard argues for a more nuanced view. Enjoying art is part of a well-lived life, so we need good reasons to give it up. And it turns out good (...) reasons are hard to find. Willard show that it's reasonable to believe that most boycotts of artists won't succeed, so most of the time there's no ethical reason to join in. Someone who manages to separate the art from the artist isn't making an ethical mistake by buying and enjoying their art. She then considers the ethical dimensions of canceling artists and so-called "cancel culture," arguing that canceling is ethically risky because it encourages moral grandstanding. Willard concludes by arguing that the popular debate has overlooked the power of art to change our lives for the good. It's of course OK to decide to give up the artwork of immoral artists, but--as Willard shows in this provocative little volume--it's OK to continue to enjoy their art, as well. Key Features Offers accessible discussions of complicated philosophical topics like aesthetic value, collective action problems, and epistemic justice Provides a unique perspective and underexplored argument on the popular issue of cancellation Explores the role of aesthetic value in our lives, including its relation to our ethical decisions and our well being. (shrink)

This 1997 book was the first English translation of all of Kant's writings on moral and political philosophy collected in a single volume. No other collection competes with the comprehensiveness of this one. As well as Kant's most famous moral and political writings, the Groundwork of the Metaphysics of Morals, the Critique of Practical Reason, the Metaphysics of Morals, and Toward Perpetual Peace, the volume includes shorter essays and reviews, some of which have never been translated before. The volume has (...) been furnished with a substantial editorial apparatus including translator's introductions and explanatory notes to each text by Mary Gregor, and a general introduction to Kant's moral and political philosophy by Allen Wood. There is also an English-German and German-English glossary of key terms. (shrink)

This 1997 book was the first English translation of all of Kant's writings on moral and political philosophy collected in a single volume. No other collection competes with the comprehensiveness of this one. As well as Kant's most famous moral and political writings, the Groundwork of the Metaphysics of Morals, the Critique of Practical Reason, the Metaphysics of Morals, and Toward Perpetual Peace, the volume includes shorter essays and reviews, some of which have never been translated before. The volume has (...) been furnished with a substantial editorial apparatus including translator's introductions and explanatory notes to each text by Mary Gregor, and a general introduction to Kant's moral and political philosophy by Allen Wood. There is also an English-German and German-English glossary of key terms. (shrink)

Renowned philosopher Mary Midgley explores the remarkable gap that has opened up between our own understanding of our sense of our self and today's scientific orthodoxy that claims the self to be nothing more than an elaborate illusion. Bringing her formidable acuity and analytic skills to bear, she exposes some very odd claims and muddled thinking on the part of cognitive scientists and psychologists when it comes to talk about the self. Well-known philosophical problems in causality, subjectivity, empiricism, free (...) will and determinsim are shown to have been glossed over by scientists claiming that the self is no more than a jumble of brain-cells. Midgley argues powerfully and persuasively that the rich variety of our imaginative life cannot be contained in the narrow bounds of a highly puritanical materialism that equates brain and self. The denial of the self has been sustained by the belief that physical science requires it, but there is not just one such pattern of thought but many others which all help to explain the different kinds of problems that arise in our life, argues Midgley. Physics' amazing contemporary successes spring from attacking problems that arise within physics, not from outside. It is no more sensible to give a physical answer to a moral problem than it is to give political answers to physical ones. 'Are you an Illusion?' is an impassioned defence of the importance of our own experiences - the subjective sources of thought - which are every bit as necessary for the world as the objective ones such as brain cells. (shrink)

Published in 1785, Immanuel Kant's Groundwork of the Metaphysics of Morals ranks alongside Plato's Republic and Aristotle's Nicomachean Ethics as one of the most profound and influential works in moral philosophy ever written. In Kant's own words, its aim is to identify and corroborate the supreme principle of morality, the categorical imperative. He argues that human beings are ends in themselves, never to be used by anyone merely as a means, and that universal and unconditional obligations must be understood as (...) an expression of the human capacity for autonomy and self-governance. As such, they are laws of freedom. This volume contains Mary Gregor's acclaimed translation of the text into English, revised by Jens Timmermann, and an accessible, updated introduction by Christine Korsgaard. (shrink)

Reading the Shape of Nature vividly recounts the turbulent early history of the Museum of Comparative Zoology at Harvard and the contrasting careers of its founder Louis Agassiz and his son Alexander. Through the story of this institution and the individuals who formed it, Mary P. Winsor explores the conflicting forces that shaped systematics in the second half of the nineteenth century. Debates over the philosophical foundations of classification, details of taxonomic research, the young institution's financial struggles, and the (...) personalities of the men most deeply involved are all brought to life. In 1859, Louis Agassiz established the Museum of Comparative Zoology to house research on the ideal types that he believed were embodied in all living forms. Agassiz's vision arose from his insistence that the order inherent in the diversity of life reflected divine creation, not organic evolution. But the mortar of the new museum had scarcely dried when Darwin's Origin was published. By Louis Agassiz's death in 1873, even his former students, including his son Alexander, had defected to the evolutionist camp. Alexander, a self-made millionaire, succeeded his father as director and introduced a significantly different agenda for the museum. To trace Louis and Alexander's arguments and the style of science they established at the museum, Winsor uses many fascinating examples that even zoologists may find unfamiliar. The locus of all this activity, the museum building itself, tells its own story through a wonderful series of archival photographs. (shrink)

The environmental crisis is most frequently viewed through the lens of science, policy, law, and economics. In recent years the moral and spiritual dimensions of this crisis are becoming more visible. Indeed, the world religions are bringing their texts and traditions, along with their ethics and practices, into dialogue with environmental problems. In a lecture delivered at the University of Utah, Tucker explores this growing movement and highlights why it holds great promise for long term changes for the flourishing of (...) the Earth community. Mary Evelyn Tucker delivered this lecture on April 11, 2013, at the 18th annual symposium sponsored by the Wallace Stegner Center for Land, Resources and the Environment at the S. J. Quinney College of Law, The University of Utah. (shrink)

The works of Mary Wollstonecraft ranged from the early Thoughts on the Education of Daughters to The Female Reader, a selection of texts for girls, and included two novels. But her reputation is founded on A Vindication of the Rights of Woman of 1792. This treatise is the first great document of feminism—and is now accepted as a core text in western tradition. It is not widely known that the germ of Wollstonecraft's great work came out of an earlier (...) and much shorter vindication—A Vindication of the Rights of Men , written in the context of the issues raised by the French Revolution. This edition, which follows the model of other Broadview Editions in including a range of materials that help the reader to see the work in the context of its era out of which it emerged, is arranged chronologically, opening with Wollstonecraft's "other vindication." It also includes a wide range of other documents in appendices, as well as a comprehensive and authoritative introduction, chronology, and full index. (shrink)

"Charming, interesting, thought-provoking and a great read." Rosalind Hursthouse The daughter of a pacifist rector who answered "No!" when his congregation asked him "Is everything in the bible true?", perhaps Mary Midgley was destined to become a philosopher. Yet few would have thought this inquisitive, untidy, nature-loving child would become "one of the sharpest critical pens in the west." This is her remarkable story. Probably the only philosopher to have been in Vienna on the eve of its invasion by (...) Nazi Germany in 1938 and dance in Trafalgar Square on VE day seven year later, she studied philosophy at Oxford in the same year as Iris Murdoch, Elizabeth Anscombe and Philippa Foot, all of whom became close friends. Midgley tells us in vivid and humorous fashion how they cut a swathe through the arid landscape of 1950s British philosophy, writing and arguing - often with each other - about the grand themes of character, beauty and the meaning of rudeness while the spectral figure of Ludwig Wittgenstein hovered in the background. She also charts the highs and lows of philosophy and academia in Britain. On joining the Reading philosophy department on £400 a year in 1949, she doubled its staff complement. But her many years at Newcastle University - where Mike Brearley, who later captained England at cricket, also used to teach - were rewarded with the closure of the philosophy department in the 1980s. The mother of three children, her journey is also one of a woman who in the 1950s and 1960s was fighting to combine a professional career with raising a family. In startling contrast to many of the academic stars of her generation, we learn that Midgley nearly became a novelist and started writing philosophy only when in her fifties, suggesting that Minerva's owl really does fly at dusk. Plainly told like her philosophy, this is an elegiac and moving account of friendships found and lost, bitter philosophical battles and of a profound love of teaching all too rarely acknowledged today. (shrink)

A History of Women Philosophers, Volume I: Ancient Women Philoophers, 600 B.C. - 500 A.D., edited by Mary Ellen Waithe, is an important but somewhat frustrating book. It is filled with tantalizing glimpses into the lives and thoughts of some of our earliest philosophical foremothers. Yet it lacks a clear unifying theme, and the abrupt transitions from one philosopher and period to the next are sometimes disconcerting. The overall effect is not unlike that of viewing an expansive landscape, illuminated (...) only by a few tiny spotlights. (shrink)

Background:Clinical investigation is a growing field employing increasing numbers of nurses. This has created a new specialty practice defined by aspects unique to nursing in a clinical research context: the objectives, setting, and nature of the nurse–participant relationship. The clinical research nurse role may give rise to feelings of ethical conflict between aspects of protocol implementation and the duty of patient advocacy, a primary nursing responsibility. Little is known about whether research nurses experience unique ethical challenges distinct from those experienced (...) by nurses in traditional patient-care settings.Research objectives:The purpose of the study was to describe the nature of ethical challenges experienced by clinical research nurses within the context of their practice.Research design:The study utilized a qualitative descriptive design with individual interviews.Participants and research context:Participating nurses self-identified as having experienced ethical challenges during screening. The majority were Caucasian, female, and worked in outpatient settings. Approximately 50% had > 10 years of research experience.Ethical considerations:The human subjects review board approved the study. Written informed consent was obtained.Findings:Predominant themes were revealed: the inability to provide a probable good, or/do no harm, and dual obligations. The following patterns and subthemes emerged: conflicted allegiances between protocol implementation, needs of the participant, desire to advance science, and tension between the nurse–patient therapeutic relationship versus the research relationship.Discussion:Participants described ethical challenges specific to the research role. The issues are central to the nurse–participant relationship, patient advocacy, the nurse’s role in implementing protocols, and/or advancing science.Conclusion:Ethical challenges related to the specialized role of clinical research nurses were identified. More research is warranted to fully understand their nature and frequency and to identify support systems for resolution. (shrink)